Clinical Outcomes After Discontinuation of Thyroid Hormone Replacement - A Systematic Review and Meta-Analysis.

CONCLUSIONS: Low quality evidence suggests that up to a third of patients remained euthyroid after LT4 discontinuation, with a higher proportion of patients with an initial diagnosis of subclinical hypothyroidism remaining euthyroid than patients with an initial diagnosis of overt hypothyroidism. A deprescribing framework focusing on adequate selection of patients for deprescribing LT4 and a systematic process is warranted to guide clinicians in re-evaluating the need for LT4 in their patients. PMID: 33161885 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research