Induced liver regeneration enhances CRISPR/Cas9-mediated gene repair

(Mary Ann Liebert, Inc./Genetic Engineering News) Use of thyroid hormone to boost hepatocyte proliferation enhanced the efficiency of CRISPR/Cas9-mediated gene correction in the mouse liver. This dietary induction of hepatocyte regeneration may be a viable clinical strategy to enhance gene repair in the liver.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news