Boron neutron capture therapy using cyclotron-based epithermal neutron source and borofalan(10B) for recurrent or locally advanced head and neck cancer (JHN002): An open-label phase II trial

Boron neutron capture therapy (BNCT) is a unique cell-selective cancer treatment technique in which tumor cells are irradiated from the inside with heavy particles produced by a10B(n, α)7Li nuclear transmutation reaction between boron-10 atoms (10B) and thermal neutrons.[1–3] The released α particles and lithium (Li) recoil nuclei produce energy to the surroundings in the range of 9 μm and 5 μm, respectively.

Source: Radiotherapy and Oncology - November 10, 2020 Category: Radiology Authors: Katsumi Hirose, Akiyoshi Konno, Junichi Hiratsuka, Seiichi Yoshimoto, Takahiro Kato, Koji Ono, Naoki Otsuki, Jun Hatazawa, Hiroki Tanaka, Kanako Takayama, Hitoshi Wada, Motohisa Suzuki, Mariko Sato, Hisashi Yamaguchi, Ichiro Seto, Yuji Ueki, Susumu Iketan Tags: Original Article Source Type: research