Shedding new light on the origin of metastases

(Universit é de Gen è ve) Before an effective treatment can be devised, we have to be able to understand the specific effect of an anti-cancer substance on the cell type that produces metastases in the cellular heterogeneity of tumours. A team from the University of Geneva used spiked-scRNAseq that links the transcriptomic to single cell metastatic phenotypes of colon cancer tumour cells. The importance of the VSIG1 gene involved in intercellular interactions has been identified: it prevents metastases.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news