676 Platypnea-Orthodeoxia Syndrome: Key Pathogenetic Role of Patent Foramen Ovale (PFO) and Dramatic Response to PFO Closure

PFO-associated platypnea-orthodeoxia syndrome (POS) is characterised by dyspnoea and hypoxaemia when upright. The pathogenesis is thought to involve an increase in right atrial pressure or change in degree of right to left shunting with upright posture.

Source: Heart, Lung and Circulation - November 8, 2020 Category: Cardiology Authors: F. Othman, N. Collins, B. Bailey, E. Lau, D. Tanous, K. Rao, D. Celermajer, R. Cordina Source Type: research