Methane supplementation improves graft function in experimental heart transplantation

: Maintenance of cell viability during cold storage is a key issue in organ transplantation. Methane (CH4) bioactivity has recently been recognised in ischaemia/reperfusion conditions; we therefore hypothesised that cold storage in CH4-enriched preservation solution can provide an increased defence against organ dysfunction during experimental heart transplantation (HTX).

Source: The Journal of Heart and Lung Transplantation - November 7, 2020 Category: Transplant Surgery Authors: K álmán Benke, Dávid Kurszán Jász, Ágnes Lilla Szilágyi, Bálint Baráth, Eszter Tuboly, Anett Roxána Márton, Petra Varga, Árpád Mohácsi, Anna Szabó, Zsófia Széll, Mihály Ruppert, Tamás Radovits, Gábor Szabó, Béla Merkely, Petra Hartma Source Type: research