Autoantigen Presentation by Splenic Dendritic Cells is Required for RBC-specific Autoimmunity.

CONCLUSION: These data suggest that if erythrocyte T cell tolerance fails, DCs are capable of initiating autoimmune responses. As such, targeting DCs may be a fruitful strategy for AIHA therapies.
PMID: 33151564 [PubMed - as supplied by publisher]

Source: Transfusion - November 5, 2020 Category: Hematology Authors: Richards AL, Qiu A, Dei Zotti F, Sheldon K, Usaneerungrueng C, Gruber DR, Hudson KE Tags: Transfusion Source Type: research