Role of lipocalin-2 in extracellular peroxiredoxin 2-induced brain swelling, inflammation and neuronal death.
In conclusion, intracerebral injection of PRX-2 upregulates LCN-2, and LCN-2 is crucial in the effects of PRX-2 on neutrophil infiltration and microglia/macrophage activation, and ultimately brain damage.
PMID: 33129840 [PubMed - as supplied by publisher]
Source: Experimental Neurology - Category: Neurology Authors: Zhang J, Novakovic N, Hua Y, Keep RF, Xi G Tags: Exp Neurol Source Type: research