Correlation between IL-31 and sCD40L plasma levels in Fingolimod-treated patients with Relapsing-Remitting Multiple Sclerosis (RRMS)

Multiple Sclerosis (MS) is a chronic, autoimmune, demyelinating disease of the central nervous system (CNS). Currently, several protocols are described for the different phases of MS. In this longitudinal study, we aim to quantify the concentration of plasma cytokines of MS patients treated with Fingolimod alone or after Glatiramer Acetate (GA) or Interferon-beta (IFN- β), in order to compeer both treatments and describes if it is possible to use them as biomarkers.

Source: Journal of Neuroimmunology - November 5, 2020 Category: Allergy & Immunology Authors: Marcus Vin ícius Magno Gonçalves, Wesley Nogueira Brandão, Carla Longo, Jean Pierre Schatzmann, Giordani Rodrigues dos Passos, Gabriela Löw Pagliarini, Osvaldo Jose Moreira do Nascimento, Daniel Rodrigo Marinowic, Denise Cantarelli Machado, Jefferson Source Type: research