New insights on Fak and Fak inhibitors.

CONCLUSION: All reported results evidenced that additional studies are necessary to design and synthesize new selective and more active compounds, although promising informations have been obtained from associations between Fak inhibitors and other different anti-cancer drugs. In addition, the other important roles evidenced, both at nuclear level and in non-cancerous cells, make this protein an increasingly important target in pharmaceutical chemistry. PMID: 33143618 [PubMed - as supplied by publisher]
Source: Current Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Med Chem Source Type: research