EUS-guided fine-needle injection for pancreatic cancer: back to the future

In this issue of Gastrointestinal Endoscopy, Lee et  al1 report a phase I trial of EUS-guided fine-needle injection (EUS-FNI) of modified adenovirus with “double suicide” genes, a second-generation oncolytic virus, for locally advanced pancreatic cancer. The treatment was safe without dose-limiting toxicity during the first 8 weeks; partial resp onse was seen in 1 patient, and the disease was stable in the remaining 8 patients at 12 weeks.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Original article Source Type: research