High frequency ultrasound assessment of systemic sclerosis skin involvement: intra-observer repeatability and relationship with clinician assessment and dermal collagen content.

CONCLUSION: Our data demonstrates excellent reproducibility and reassuring convergent validity with dermal collagen content. Detection of subclinical abnormalities is an additional benefit of HFUS. The observed correlations with collagen quantification support further investigation of HFUS as an alternative to mRSS in clinical trial settings. PMID: 33132218 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33132218?dopt=Abstract

Source: J Rheumatol - November 1, 2020 Category: Rheumatology Authors: Flower VA, Barratt SL, Hart DJ, Mackenzie AB, Shipley JA, Ward SG, Pauling JD Tags: J Rheumatol Source Type: research