TGF- β1 decreases CHOP expression and prevents cardiac fibroblast apoptosis induced by endoplasmic reticulum stress.

In conclusion, TGF-β1 partially protects CF apoptosis induced by sI/R or Tn, through a mechanism that would involve ER stress.
PMID: 33127435 [PubMed - as supplied by publisher]

Source: Toxicology in Vitro - October 27, 2020 Category: Toxicology Authors: Olivares-Silva F, Espitia-Corredor J, Letelier A, Vivar R, Parra-Flores P, Olmedo I, Montenegro J, Pardo-Jiménez V, Díaz-Araya G Tags: Toxicol In Vitro Source Type: research