Extracellular ATP modulates podocyte function through P2Y purinergic receptors and pleiotropic effects on AMPK and cAMP/PKA signaling pathways.

We describe a protection mechanism for the glomerular barrier linked to reduced oxidative stress and reestablished energy balance.
PMID: 33122160 [PubMed - as supplied by publisher]

Source: Archives of Biochemistry and Biophysics - October 22, 2020 Category: Biochemistry Authors: Szrejder M, Rachubik P, Rogacka D, Audzeyenka I, Rychłowski M, Angielski S, Piwkowska A Tags: Arch Biochem Biophys Source Type: research