Seizures in autoimmune encephalitis: Findings from an EEG pooled analysis

Autoimmune encephalitis (AEs) encompasses a variable spectrum of clinical manifestations pointing to a widespread brain involvement, well beyond the limbic system alone [1]. Besides mental status alterations, cognitive deficits and behavioral/psychiatric disorders, seizures are part of the clinical core of AE [2], and often represent the most alarming and impressive sign at the disease onset, leading the patients to seek medical advice. The subacute onset of seizures, especially in elderly subjects, urges the need to investigate (and eventually rule out) numerous possible etiologies or mimics, ranging from vascular accidents and toxic-metabolic encephalopathies to neurodegenerative diseases.

Source: Seizure: European Journal of Epilepsy - October 30, 2020 Category: Neurology Authors: Alessandra Morano, Martina Fanella, Emanuele Cerulli Irelli, Francesca A. Barone, Giacomo Fisco, Biagio Orlando, Mariarita Albini, Jinane Fattouch, Mario Manfredi, Sara Casciato, Giancarlo Di Gennaro, Anna Teresa Giallonardo, Carlo Di Bonaventura Source Type: research