Cell-free nucleic acid patterns in disease prediction and monitoring —hype or hope?

This article highlights the involvement of circulating CFNAs in local and systemic processes dealing with the question, whether specific patterns of CFNAs in blood, their detection, quantity and quality (such as  their methylation status) might be instrumental to predict a disease development/progression and could be further utilised for accompanying diagnostics, targeted prevention, creation of individualised therapy algorithms, therapy monitoring and prognosis. Presented considerations conform with princ iples of 3P medicine and serve for improving individual outcomes and cost efficacy of medical services provided to the population.
Source: EPMA Journal - Category: International Medicine & Public Health Source Type: research