New in vitro model of Mycobacterium tuberculosis dormancy

Conclusions: Culture of Mtb under conditions of deprivation of the above-mentioned components results in the induction of Mtb with phenotypical signs of dormant state. This method of induction of dormant phenotype of Mtb may be used as new in vitro model to study Mtb dormancy phenomenon including susceptibility testing of dormant form of Mtb to anti-TB drugs.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Tuberculosis Source Type: research