Patterns of changes of the flow-volume curve in Duchenne Muscular Dystrophy (DMD)

Conclusions: In DMD, flows and volumes are significantly lower than predicted since childhood, starting to be halved by the age of 15, while the flow-volume loop area three years earlier. The flow-volume loop area seems to be a promising index to early identify the deterioration of lung function in DMD, since it combined both volume and flow data.

Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: LoMauro, A., Marchi, E., D'Angelo, G., Aliverti, A. Tags: Paediatric respiratory physiology and sleep Source Type: research