Neutrophil Extracellular Traps (NETs) increase mucus viscoelasticity

Conclusion: We show that exposing airway mucus to NETs increases the viscoelasticity of airway mucus and that this may be due, in part, to oxidative stress. This implicates a role for NETs formation in the airways as an underlying mechanism in airway mucus obstruction.

Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Linssen, R. S. N., Chai, G., Ma, J., Kummarapurugu, A., Van Woensel, J. B. M., Bem, R. A., Kaler, L., Duncan, G., Zhou, L., Rubin, B. K., Xu, Q. Tags: Paediatric respiratory infection and immun. Source Type: research