Yale finds neuron behind fatal anorexia, and solution in high-fat diet

Inhibition of a neuron that helps the body access alternative forms of fuel may be one cause behind death from anorexia nervosa, Yale research finds.
Source: Yale Science and Health News - Category: Universities & Medical Training Source Type: news

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Conditions:   Anorexia Nervosa;   Bulimia Nervosa Intervention:   Sponsor:   University of California, San Diego Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: Findings suggest that loss of control is more clinically relevant in terms of associations with eating disorder and depressive symptoms in middle-aged women.LEVEL OF EVIDENCE: Level V based on descriptive studies.PMID:34558018 | DOI:10.1007/s40519-021-01305-2
Source: Eating and weight disorders : EWD - Category: Eating Disorders & Weight Management Authors: Source Type: research
AbstractTropical theileriosis is one of the major causes of newborn calves mortality. Observation of clinical manifestations is important while making the presumptive/tentative diagnosis of tropical theileriosis in newborn calves. The phenotypic and haemato-biochemical appraisals of tropical theileriosis could be of great help to make a holistic therapeutic plan for diseased newborn calves. Therefore, the present study aimed to evaluate the haemato-biochemical and phenotypic diagnostic markers of tropical theileriosis in newborn calves. A total of 43 newborn calves naturally infected withTheileria annulata and 16 age-match...
Source: Tropical Animal Health and Production - Category: Veterinary Research Source Type: research
We present the main results of the different studies separately and then comment on some similarities and differences in the findings. We find that the results of these studies are complementary on certain aspects of functioning found in anorexia nervosa as compared with other categories of eating disorders. Both sets of studies underline the self-centeredness of anorexic patients with their difficulty in communicating their feelings and thoughts. In both types of study, treatment is understood as relying on an integrative and multidisciplinary model that seeks to modify the eating behaviors and to improve ego functions in...
Source: Rorschachiana - Category: Psychiatry & Psychology Source Type: research
CONCLUSION: Results from the milestones suggest self-reported cognitive-behavioral flexibility is not a strong determinant of everyday function. Results from the subjective WSAS function measure and the more objective functional milestones were not consistent. To obtain a more balanced assessment of everyday functioning in AN, both subjective and objective measures should be considered.LEVEL OF EVIDENCE: Level III Case-control analytic study.PMID:34550546 | PMC:PMC8456687 | DOI:10.1007/s40519-021-01300-7
Source: Eating and weight disorders : EWD - Category: Eating Disorders & Weight Management Authors: Source Type: research
ConclusionSOX100 combined with trastuzumab was effective with a favorable safety profile in patients with HER2-positive AGC.
Source: Journal of Gastrointestinal Cancer - Category: Cancer & Oncology Source Type: research
DiscussionOur data suggest that interval treatment for AN is effective and may even be superior to conventional single inpatient treatment. Given the observational nature of this study, however, controlled studies are necessary to corroborate these findings.
Source: Brain and Behavior - Category: Neurology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Aust N Z J Psychiatry. 2021 Sep 18:48674211047189. doi: 10.1177/00048674211047189. Online ahead of print.ABSTRACTOBJECTIVE: Recent research has suggested that a type of atypical eye movement, called square wave jerks, together with anxiety, may distinguish individuals with anorexia nervosa from those without anorexia nervosa and may represent a biomarker and endophenotype for the illness. The aim of this study was to identify the presence of this proposed marker in individuals currently with anorexia nervosa relative to healthy controls, and to identify the state independence and heritability of this putative marker by exp...
Source: The Australian and New Zealand Journal of Psychiatry - Category: Psychiatry Authors: Source Type: research
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Source: eMedicineHealth.com - Category: General Medicine Source Type: news
A 72-year-old woman presented with a 6-month history of anorexia, weight loss (-14kg) and myalgia in upper limbs. Clinical examination showed moderate proximal muscle weakness in upper limbs and crepitation at lung auscultation, but no skin rash nor joint involvement. Biological assessment disclosed increased C-reactive protein (68 µM) and creatine-kinase (3800 U/l) serum levels and anti-nuclear and -PL7 autoantibodies at immunological screening. Thoracic CT-scan showed abnormalities consistent with interstitial pneumonia.
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research
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