Efficacy, renal safety and tolerability of sodium-glucose cotransporter 2 inhibitors (SGLT2i) in elderly patients with type 2 diabetes: A real-world experience

The number of patients with type 2 diabetes mellitus (T2DM) is dramatically increasing worldwide, especially among people over the age of 65 years [1 –3]. Treatment of T2DM in older adults requires careful consideration, since the risk of comorbidities and hypoglycemic events increases with age [4]. Moreover, older diabetic patients are also prone to cognitive impairment, depression, frailty, and adverse events from polypharmacy that can furthe r complicate their management. For these reasons recent guidelines recommend an individualized approach to treating T2DM in older adults that balances achieving glycemic control with minimal risks to the individual’s safety [5].
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Original research Source Type: research