GSE153282 Primate heart regeneration via migration and fibroblast repulsion by human heart progenitors

Contributors : Gianluca Santamaria ; Alessandra MorettiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiens ; Macaca fascicularisIn the present study, scRNAseq was carried out to establish a molecular roadmap for HVP specification and maturation during heart repair as well as HVP properties in response to acute cardiac injury.Transcriptional profiling by scRNAseq was performed at various timepoints during Human ventricular progenitor-differentiation at D0 and D3 towards cardiomyocytes at D21 that were co-cultured on chimeric human- NHP heart slices. scRNAseq was also performed for HVPs and NHP cells at 24h and 48 h after RFA- induced injury.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Macaca fascicularis Source Type: research