Inflammation, cytomegalovirus and the growth hormone axis in HIV-exposed uninfected Zimbabwean infants
Conclusion:
Overall, we found evidence for greater disruption of the GH axis in HEU compared with HIV-unexposed infants as early as 6 weeks of age, suggesting a role for reduced IGF-1 in mediating growth impairment in HEU infants. Inflammation and coinfections may be drivers of growth impairment in HEU infants by disrupting the GH axis.
Source: AIDS - Category: Infectious Diseases Tags: BASIC SCIENCE: CONCISE COMMUNICATION Source Type: research
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