The Role of Hypothermia in Large Hemispheric Infarction: A Systematic Review and Meta-Analysis

Conclusions: This meta-analysis suggested that hypothermia was not associated with mortality in LHI patients. However, it was associated with the improvement of neurological outcome, but with a higher risk of adverse events during treatment. Future studies are needed to demonstrate the efficacy and safety of hypothermia for LHI. The protocol for this systematic review was obtained from PROSPERO (registration number: CRD42018111761).
Source: Frontiers in Neurology - Category: Neurology Source Type: research