IJERPH, Vol. 17, Pages 7810: Heritability and Environmental Correlation of Phase Angle with Anthropometric Measurements: A Twin Study
IJERPH, Vol. 17, Pages 7810: Heritability and Environmental Correlation of Phase Angle with Anthropometric Measurements: A Twin Study
International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17217810
Authors:
Daisuke Matsumoto
Fujio Inui
Chika Honda
Rie Tomizawa
Mikio Watanabe
Karri Silventoinen
Norio Sakai
Bioelectrical impedance analysis (BIA)-derived phase angle (PhA) is a valuable parameter to assess physical health. However, the genetic and environmental aspects of PhA are not yet well understood. The present study aimed to estimate the heritability of PhA and investigate the relationships between PhA and anthropometric measurements. PhA and skeletal muscle mass index (SMI) were examined using multi-frequency BIA in 168 Japanese twin volunteers (54 males and 114 females; mean age = 61.0 ± 16.5 years). We estimated the narrow-sense heritability of these parameters and the genetic and environmental relationships between them using a genetic twin modeling. For the PhA, 51% (95% confidence interval: 0.33, 0.64) of the variance was explained by additive genetic effects, and 49% (95% confidence interval: 0.36, 0.67) was explained by unique environmental effects. The heritability of PhA was lower than the height, body weight, and body mass index. PhA shared almost no genetic variation with anthropometric measurements and SMI but shared an environmental variation (14%) with SMI. These findings suggest that the genes ...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Daisuke Matsumoto Fujio Inui Chika Honda Rie Tomizawa Mikio Watanabe Karri Silventoinen Norio Sakai Tags: Article Source Type: research
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