Corticosteroid receptor rebalancing alleviates critical illness-related corticosteroid insufficiency after traumatic brain injury by promoting paraventricular nuclear cell survival via Akt/CREB/BDNF signaling

We previously found that high-dose methylprednisolone increased the incidence of critical illness-related corticosteroid insufficiency (CIRCI) and mortality in rats with traumatic brain injury (TBI), whereas l...

Source: Journal of Neuroinflammation - October 25, 2020 Category: Neurology Authors: Bin Zhang, Miao Bai, Xiaojian Xu, Mengshi Yang, Fei Niu, Fei Gao and Baiyun Liu Tags: Research Source Type: research