High-Resolution pO2 Imaging Improves Quantification of the Hypoxic Fraction in Tumors During Radiation therapy

The extreme microscopic heterogeneity of tumors makes it difficult to characterize tumor hypoxia. We evaluated how changes in the spatial resolution of oxygen imaging could alter measures of tumor hypoxia and their correlation to radiation therapy response.

Source: International Journal of Radiation Oncology * Biology * Physics - September 28, 2020 Category: Radiology Authors: Xu Cao, Srinivasa Rao Allu, Shudong Jiang, Jason R. Gunn, BS, Cuiping Yao, PhD, Jing Xin, PhD, Petr Bruza, PhD, David J. Gladstone, ScD, Lesley A. Jarvis, MD, PhD, Jie Tian, PhD, Harold M. Swartz, MD, MSPH, PhD, Sergei A. Vinogradov, PhD, Brian W. Pogue, Tags: Clinical Investigation Source Type: research