Levothyroxine and insulin requirement in autoimmune polyglandular type 3 syndrome: a real-life study

ConclusionPatients with APS-3 show lower insulin requirement and higher levothyroxine requirement than T1DM and AH alone, respectively. Levothyroxine treatment and VAI affect insulin and levothyroxine requirement, respectively, in APS-3. In T1DM, adipose tissue dysfunction, indirectly expressed by high VAI, is associated with an increased insulin requirement, while circulating irisin levels influence the levothyroxine requirement in AH.

Source: Journal of Endocrinological Investigation - October 24, 2020 Category: Endocrinology Source Type: research