Analysis of pharmacogenomic factors for chemotherapy-induced nausea and vomiting in patients with breast cancer receiving doxorubicin and cyclophosphamide chemotherapy

ConclusionNo significant association was found betweenABCB1 2677G  >  T/A and CR0 –24. However, it was observed that the polymorphism ofTACR1, which encodes the neurokinin 1 receptor, might be a potential genetic risk factor for the development of delayed phase CINV.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research