TRIM16 protects human periodontal ligament stem cells from oxidative stress-induced damage via activation of PICOT.

In conclusion, TRIM16 alleviated oxidative damage in hPDLSCs via the activation of PICOT/Akt/Nrf2 pathway, suggesting that TRIM16 could be a promising target to develop effective therapies for periodontitis.
PMID: 33091421 [PubMed - as supplied by publisher]

Source: Experimental Cell Research - October 19, 2020 Category: Cytology Authors: Zhao Y, Liu H, Xi X, Chen S, Liu D Tags: Exp Cell Res Source Type: research