Molecules, Vol. 25, Pages 4903: Total Synthesis of Cyclopiamide A Using Palladium-Catalyzed Domino Cyclization

Molecules, Vol. 25, Pages 4903: Total Synthesis of Cyclopiamide A Using Palladium-Catalyzed Domino Cyclization
Molecules doi: 10.3390/molecules25214903
Authors:
Sunhwa Park
Kye Jung Shin
Jae Hong Seo

Total synthesis of cyclopiamide A was accomplished using a palladium-catalyzed domino cyclization. Three rings in the tetracyclic skeleton of cyclopiamide A were constructed in a one-step domino reaction incorporating double carbopalladation and C-H activation.

Source: Molecules - October 23, 2020 Category: Chemistry Authors: Sunhwa Park Kye Jung Shin Jae Hong Seo Tags: Article Source Type: research