Komodo-dragon cathelicidin-inspired peptides are antibacterial against carbapenem-resistant Klebsiella pneumoniae.

Conclusion. Given the challenges of treating CRKP, identification of peptides with activity against it represents a promising avenue for further research. Given DRGN-6's similar level of activity to colistin, DRGN-6 is a promising template for the development of novel antimicrobial peptide-based therapeutics.
PMID: 33084564 [PubMed - as supplied by publisher]

Source: Journal of Medical Microbiology - October 21, 2020 Category: Microbiology Authors: Hitt SJ, Bishop BM, van Hoek ML Tags: J Med Microbiol Source Type: research