Elucidation of the mechanisms and molecular targets of Qishen Yiqi formula for the treatment of pulmonary arterial hypertension using a bioinformatics/network topology-based strategy.

CONCLUSION: An integrative investigation based on network pharmacology may elucidate the multicomponent synergistic mechanisms of QSYQ in PAH and lay a foundation for further animal experiments, human clinical trials and rational clinical applications of QSYQ.
PMID: 33076804 [PubMed - as supplied by publisher]

Source: Combinatorial Chemistry and High Throughput Screening - October 19, 2020 Category: Chemistry Authors: Wu P, Xie X, Chen M, Sun J, Cai L, Wei J, Yang L, Huang X, Wang L Tags: Comb Chem High Throughput Screen Source Type: research