Parkinsonism in children: Clinical classification and etiological spectrum
Infantile- and childhood-onset parkinsonism is mainly due to genetic alterations and is an exceedingly rare condition, unlike Parkinson's disease (PD), which is one of the most common neurologic disorders in adulthood. The clinical characterization of parkinsonism during early stages of neuromotor development is controversial due to the lack of consensus regarding the clinical criteria of PD or parkinsonism in the immature brain. The classification here proposed is based on a review of conditions that emerge during infancy and childhood, with key symptoms evocative of adult parkinsonism.
Source: Parkinsonism and Related Disorders - Category: Neurology Authors: Vincenzo Leuzzi, Francesca Nardecchia, Roser Pons, Serena Galosi Tags: Review article Source Type: research