Statistical Methods for Time-Dependent Variables in Hematopoietic Cell Transplantation Studies

A time-dependent variable occurs in hematopoietic cell transplantation (HCT) studies when a value of a variable changes over time. For example, the patient's infection status after HCT is a time-dependent variable. At any time post-HCT, a patient's current infection status at time t has 2 values, infected or not infected, or rather, no infection before time t and infection before time t. These infections are often a cause of death, and after getting infections, patients often show worse outcomes compared to before getting infections [1,2].
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research