Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer ’s disease

To prevent or delay the onset of Alzheimer ’s disease (AD), we must understand its molecular basis. The great majority of AD cases arise sporadically with a late onset after 65 years of age (LOAD). However, rar...

Source: Molecular Brain - October 19, 2020 Category: Neuroscience Authors: Karissa Barthelson, Stephen Martin Pederson, Morgan Newman and Michael Lardelli Tags: Research Source Type: research