Implant of mesenchymal cells decreases acute cellular rejection in small bowel transplantation.

Conclusions: The local implantation of AD-MSC in the anastomosis and the intestinal lumen can induce a regulatory immune response, by increasing the percentages of Treg cells and TGb-1 levels, leading to a lower risk of acute rejection by cell mediation, in the first 7 days of the intestinal transplant. We think that the implantation of AD-MSCs, in the anastomoses and in the lumen of the donor intestine, could give rise to a chimera of donor-recipient cells. PMID: 33064706 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/33064706?dopt=Abstract

Source: Cirugia y Cirujanos - October 20, 2020 Category: Surgery Authors: Navarro-Zorraquino M, Pastor C, Stringa P, Soria J, Hernández F, López-Santamaría M, García-Alvarez F Tags: Cir Cir Source Type: research