Benefit of hospital admission for detecting serious adverse events among emergency department patients with syncope: a propensity-score-matched analysis of a multicentre prospective cohort.

Benefit of hospital admission for detecting serious adverse events among emergency department patients with syncope: a propensity-score-matched analysis of a multicentre prospective cohort.
CMAJ. 2020 Oct 13;192(41):E1198-E1205
Authors: Krishnan RJ, Mukarram M, Ghaedi B, Sivilotti MLA, Le Sage N, Yan JW, Huang P, Hegdekar M, Mercier E, Nemnom MJ, Calder LA, McRae AD, Rowe BH, Wells GA, Thiruganasambandamoorthy V
Abstract
BACKGROUND: The benefit of hospital admission after emergency department evaluation for syncope is unclear. We sought to determine the association between hospital admission and detection of serious adverse events, and whether this varied according to the Canadian Syncope Risk Score (CSRS).
METHODS: We conducted a secondary analysis of a multicentre prospective cohort of patients assessed in the emergency department for syncope. We compared patients admitted to hospital and discharged patients, using propensity scores to match 1:1 for risk of a serious adverse event. The primary outcome was detection of a serious adverse event in hospital for admitted patients or within 30 days after emergency department disposition for discharged patients.
RESULTS: We included 8183 patients, of whom 743 (9.1%) were admitted; 658/743 (88.6%) were matched. Admitted patients had higher odds of detection of a serious adverse event (odds ratio [OR] 5.0, 95% confidence interval [CI] 3.3-7.4), nonfatal arrhythmia (OR 5.1, 9...

Source: cmaj - October 13, 2020 Category: General Medicine Authors: Krishnan RJ, Mukarram M, Ghaedi B, Sivilotti MLA, Le Sage N, Yan JW, Huang P, Hegdekar M, Mercier E, Nemnom MJ, Calder LA, McRae AD, Rowe BH, Wells GA, Thiruganasambandamoorthy V Tags: CMAJ Source Type: research