Macrophage Biology in Cardiovascular Diseases.

Macrophage Biology in Cardiovascular Diseases.
Arterioscler Thromb Vasc Biol. 2020 Oct 15;:ATVBAHA120313584
Authors: Khoury MK, Yang H, Liu B
Abstract
Macrophages have key functional role in the pathogenesis are various cardiovascular diseases, such as atherosclerosis and aortic aneurysm. Their accumulation within the vessel wall leads to sustained local inflammatory responses characterized by secretion of chemokines, cytokines, and matrix protein degrading enzymes. Here, we summarize recent findings on macrophage contribution to cardiovascular disease published in ATVB. In this issue, we focus on the origin, survival/death, and phenotypic switching of macrophages within vessel walls.
PMID: 33054391 [PubMed - as supplied by publisher]

Source: Arteriosclerosis, Thrombosis and Vascular Biology - October 15, 2020 Category: Cardiology Authors: Khoury MK, Yang H, Liu B Tags: Arterioscler Thromb Vasc Biol Source Type: research