CD137 Ligand-CD137 Interaction is Required For Inflammasome-Associated Brain Injury Following Ischemic Stroke

In conclusion, our data provide evidence for the first time that the CD137L-CD137 axis contributes to brain injury and neurological deficits by activating the inflammasome signaling pathway following ischemic stroke.

http://link.springer.com/10.1007/s12017-020-08623-1

Source: NeuroMolecular Medicine - October 19, 2020 Category: Neurology Source Type: research