Hospitalization in South African Adolescents With Perinatally Acquired HIV on Antiretroviral Therapy

We described the incidence and causes of hospitalization in participants enrolled in the Cape Town Adolescent Antiretroviral Cohort in South Africa. Methods: Data collected from July 2013 to October 2018 from PHIV+ and HIV− adolescents were analyzed. Participants were assessed every 6 months and data on intercurrent hospitalization were abstracted. Causes of hospitalizations were classified according to ICD-10 codes. Descriptive statistics, time-to-event analysis and Poisson regression were used to describe causes and incidence and to determine incidence rate ratios for factors associated with hospitalization. Results: Five hundred fifteen PHIV+ and 109 HIV− participants had a median follow-up of 4.1 years [interquartile range (IQR): 3.7–4.6]. At enrollment HIV+ participants had a median duration of ART of 7.6 years (IQR: 4.6–9.2), median CD4 count of 713 cells/mm3 (IQR: 561.0–957.5) and 387 (75%) had a viral load
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: HIV Reports Source Type: research