More precise dosing of acenocoumarol for better control in patients aged above 80 years, a randomised controlled pilot study

Many elderly patients are confined to treatment with vitamin K antagonists (VKA) instead of direct oral anticoagulants (DOACs). However, quality of VKA treatment declines with age. This might be caused by the lower dose requirements with increasing age, which result in relatively large day-by-day VKA dose differences. Therefore, more precise dosing with smaller dose increments might improve quality of VKA treatment in the elderly.

Source: Thrombosis Research - October 16, 2020 Category: Hematology Authors: M. Piersma-Wichers, J.H.A. van Miert, N.J.G.M. Veeger, H.A.M. Kooistra, K. Meijer Tags: Letter to the Editors-in-Chief Source Type: research