Methylation status of long interspersed element-1 in advanced gastric cancer and its prognostic implication

Conclusion Our findings indicate that the discrepancy in the methylation level of L1 between fresh tissue and formalin-fixed paraffin-embedded tissue samples depends on the CpG sites considered, and that the methylation status of L1 at CpG sites 1 and 4 combined could be utilized as a prognostic parameter for advanced gastric cancers.
Source: Gastric Cancer - Category: Gastroenterology Source Type: research