Clinicopathologic characteristics and outcomes of endometrial Cancer patients with mismatch repair deficiency in the era of universal Lynch syndrome screening.

CONCLUSION: MMR deficiency is associated with adverse prognostic factors and worse PFS among endometrioid tumors, particularly in early stage EC. MMR testing outside of LS screening has prognostic value, warranting consideration for inclusion as a biomarker in prospective clinical trials.
PMID: 33046272 [PubMed - as supplied by publisher]

Source: Gynecologic Oncology - October 9, 2020 Category: Cancer & Oncology Authors: Carr C, Son J, Yao M, Priyadarshini A, Marquard J, Vargas R, Michener C, AlHilli MM Tags: Gynecol Oncol Source Type: research