Effect of adding androgen deprivation therapy to permanent iodine-125 implantation with or without external beam radiation therapy on the outcomes in patients with intermediate-risk prostate cancer: A propensity score –matched analysis11ADT, androgen deprivation therapy; ASCENDE-RT, Androgen Suppression Combined with Elective Nodal and Dose Escalated Radiation Therapy; BED, biological effective dose; bFFR, biochemical failure-free rate; bFFS, biochemical failure-free survival; BT, brachytherapy; EBRT, external beam radiation therapy; CI, confidence interval; CT, computed tomography; CVD, cardiovascular disease; GS, Gleason score; IQR, interquartile range; HR, hazard ratio; LRFR, local recurrence-free rate; MVA, multivariate analysis; NCCN, National Comprehensive Cancer Network; OS, overall survival; PET, positron emission tomography; PSA, prostate-specific antigen; PSM, propensity score matching; TTMB, transperineal template-guided mapping biopsy; UVA, univariate analysis.

The purpose of the study was to evaluate the effect of adding androgen deprivation therapy (ADT) to brachytherapy with or without external beam radiation therapy on oncological outcomes in prostate cancer.
Source: Brachytherapy - Category: Cancer & Oncology Authors: Source Type: research