Medium-firm drug-candidate library of cryptand-like structures on T7 phage: Design and selection of strong binder for Hsp90

Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB01855D, CommunicationKazuto Mochizuki, Lisa Matsukura, Yuji Ito, Naoyuki Miyashita, Masumi Taki We designed and synthesized a medium-firm drug-candidate library of cryptand-like structures possessing randomized peptide linker on bacteriophage T7. From the macrocyclic library with 10^9 diversity, we obtained a binder toward... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research