Pituitary-adrenal axis hormones in early-onset versus late-onset panic disorder.

CONCLUSIONS: These findings suggest that the two onset-groups demonstrate significant differences in the hypothalamic-pituitary-adrenal axis functioning, at least when acutely-ill. Key points Early-onset panic disorder (EOPD) may differ biologically from late-onset PD (LOPD). EOPD was correlated with greater adrenocorticotropic hormone (ACTH) plasma levels. EOPD was correlated with greater dehydroepiandrosterone sulphate plasma levels. In EOPD only, ACTH levels were positively correlated with panic and anxiety symptoms. PMID: 33043745 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33043745?dopt=Abstract

Source: International Journal of Psychiatry in Clinical Practice - October 14, 2020 Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research