Appropriate chemopreventive strategy for anti-tubercular therapy related liver injury is unsettled: results from a systematic review and network meta-analysis.

CONCLUSION: N-acetyl cysteine, but not Silymarin/Silibinin, appears to be beneficial in prevention of ATT-DILI. However, the results were limited by the possible risk of bias in included studies, variable definitions of ATT-DILI and limited number and category of patients. PMID: 33043729 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33043729?dopt=Abstract

Source: Pharmacological Reviews - October 12, 2020 Category: Drugs & Pharmacology Authors: Singh AK, Verma S, Kumar-M P, Soni H, Sharma S, Sharma S, Patil A, Sharma V Tags: Expert Rev Clin Pharmacol Source Type: research