[Heart failure protection by SGLT2 inhibitors in patients with type  2 diabetes mellitus: evidence and possible mechanisms : A systematic review].

CONCLUSION: The SGLT2 inhibitors show a moderate heart failure protective effect in diabetic patients. It is likely that a nephroprotective effect with modulation of the cardiorenal interaction is an important part of the mechanism of action but this must be substantiated in further investigations. PMID: 33044563 [PubMed - as supplied by publisher]
Source: Herz - Category: Cardiology Tags: Herz Source Type: research