Leptin G-2548A and Leptin Receptor Q223R gene polymorphisms are differently associated with oxidative process in Mexican mestizo and indigenous with obesity.

CONCLUSION: It is probable that there is a synergistic effect for obesity, where the presence of oxidative stress and single nucleotide polymorphisms (SNP) of leptin and its receptor, contribute to the generation of pathological subcutaneous fat of obesity, together with the environmental conditions of the populations. PMID: 33038917 [PubMed - as supplied by publisher]
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Endocrinology Authors: Tags: Endocr Metab Immune Disord Drug Targets Source Type: research